Structure-Based Characterization of Peptide-Mediated Protein Interactions
نویسندگان
چکیده
منابع مشابه
Contextual Specificity in Peptide-Mediated Protein Interactions
Most biological processes are regulated through complex networks of transient protein interactions where a globular domain in one protein recognizes a linear peptide from another, creating a relatively small contact interface. Although sufficient to ensure binding, these linear motifs alone are usually too short to achieve the high specificity observed, and additional contacts are often encoded...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2402